For decades, Virovek has been a world leader in gene therapy and vector manufacturing.
Virovek offers custom AAV production services in Sf9 and HEK293, lentivirus and adenovirus packaging services, gene cloning services, recombinant baculoviruses, plasmid and bacmid DNA, quality control assays, and GLP manufacturing capabilities.
Virovek boasts the world’s most efficient large-scale AAV production system, capable of quickly and easily generating AAV with titers up to 1E+17 vg/mL. Prices start at just $2,310 for 1E+13 vg of custom-made AAV for academic customers, and $3,080 for industrial customers.
Partners & Customers
AAV Serotype |
Retina |
Heart |
Liver |
Lung |
CNS/Brain |
Skeletal Muscle |
Other |
---|---|---|---|---|---|---|---|
AAV1 |
X |
X |
|||||
AAV2 |
X |
X |
|||||
AAV2-Retro |
X |
||||||
AAV3A, 3B |
X |
||||||
AAV4 |
X |
X |
|||||
AAV5 |
X |
X |
Immune system |
||||
AAV6 |
X |
X |
X |
Immune system, pancreas |
|||
AAV7 |
X |
X |
X |
||||
AAV8 |
X |
X |
X |
||||
AAV9 |
X |
X |
|||||
AAVShH10 |
X |
||||||
AAVrh10 |
X |
X |
X |
||||
AAV7m8 |
X |
||||||
AAVDJ |
X |
X |
X |
Kidney, cervix, ovary, skin, fibroblast |
|||
AAVphp.b |
X |
||||||
AAVphp.eb |
X |
||||||
AAV10 |
X |
X |
X |
X |
kidney, uterus |
||
AAV11 |
X |
X |
X |
kidney, spleen, stomach |
Serotype 2 generally tranduces cells more effectively in vitro than other serotypes
All other serotypes transduce cells more effectively in vivo
BAC-to-AAV
The World’s Most Efficient Large-Scale AAV Manufacturing System
Virovek’s patented BAC-TO-AAV technology has the capability of generating over 1E+16vg of adeno-associated virus in a single run. Learn more about our technology platform and explore a wide range of applications.
All AAV-Related Specialties and Services
Custom AAV
Vector production service from 1E+13vg to 1E+17vg scale in 6+ weeks
Pre-Made AAV
Off-the shelf, immediate dispatchment, approx. default titer of 2E+13vg
HEK293
Custom AAVs in HEK293 system, from 1E+12vg to 1E+15vg
Plasmids
30ug starting at $350
Bacmids
DNA generation and pre-made bacmids with optional large-scale purification
Lentivirus
Lentivirus packaging from 1E+8 TU to 1E+12 TU
Recombinant Baculovirus
To infect Sf9 insect cells as an intermediate step in AAV production
Gene Cloning
Single-step or complex cloning strategies tailored to your needs
Quality Control Assays
A wide selection of QC assays for your AAV products