In Vivo Hepatic Reprogramming of Myofibroblasts with AAV Vectors as a Therapeutic Strategy for Liver Fibrosis Milad Rezvani, Regina Español-Suñer, Yann Malato, Laure Dumont, Andrew A. Grimm, Eike Kienle, Julia G. Bindman, Ellen Wiedtke, Bernadette Y. Hsu, Syed J. Naqvi, Robert F. Schwabe, Carlos U. Corvera, Dirk Grimm, Holger Willenbring Cell Stem...
Selective activation of a putative reinforcement signal conditions cued interval timing in primary visual cortex Cheng-Hang Liu, Jason E. Coleman, Heydar Davoudi, Kechen Zhang, Marshall G. Hussain Shuler Curr Biol. Author manuscript; available in PMC 2016 Jun 15. Published in final edited form as: Curr Biol. 2015 Jun 15; 25(12): 1551–1561. Published online...
Acute cerebellar knockdown of Sgce reproduces salient features of myoclonus-dystonia (DYT11) in mice Samantha Washburn, Rachel Fremont, Maria Camila Moreno-Escobar, Chantal Angueyra, Kamran Khodakhah eLife. 2019; 8: e52101. Published online 2019 Dec 23. doi: 10.7554/eLife.52101 PMCID: PMC6959989 ...
Aberrant Purkinje cell activity is the cause of dystonia in a shRNA-based mouse model of Rapid Onset Dystonia-Parkinsonism Rachel Fremont, Ambika Tewari, Kamran Khodakhah Neurobiol Dis. Author manuscript; available in PMC 2016 Oct 1. Published in final edited form as: Neurobiol Dis. 2015 Oct; 82: 200–212. Published online 2015 Jun 17. doi: 10.1016/j.nbd.2015.06.004 PMCID:...
Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intracerebroventricular injection Sean L. Hammond, Ashley N. Leek, Evan H. Richman, Ronald B. Tjalkens PLoS One. 2017; 12(12): e0188830. Published online 2017 Dec 15. doi: 10.1371/journal.pone.0188830 PMCID: PMC5731760 ...
BACE2, a conditional β-secretase, contributes to Alzheimer’s disease pathogenesis Zhe Wang, Qin Xu, Fang Cai, Xi Liu, Yili Wu, Weihong Song JCI Insight. 2019 Jan 10; 4(1): e123431. Published online 2019 Jan 10. doi: 10.1172/jci.insight.123431 PMCID: PMC6485359 ...
Klotho controls the brain–immune system interface in the choroid plexus Lei Zhu, Liana R. Stein, Daniel Kim, Kaitlyn Ho, Gui-Qiu Yu, Lihong Zhan, Tobias E. Larsson, Lennart Mucke Proc Natl Acad Sci U S A. 2018 Nov 27; 115(48): E11388–E11396. Published online 2018 Nov 9. doi: 10.1073/pnas.1808609115 PMCID: PMC6275534 ...
Integration of a CD19 CAR into the TCR Alpha Chain Locus Streamlines Production of Allogeneic Gene-Edited CAR T Cells Daniel T. MacLeod, Jeyaraj Antony, Aaron J. Martin, Rachel J. Moser, Armin Hekele, Keith J. Wetzel, Audrey E. Brown, Melissa A. Triggiano, Jo Ann Hux, Christina D. Pham, Victor V. Bartsevich, Caitlin...
Dystonia type 6 gene product Thap1: identification of a 50 kDa DNA-binding species in neuronal nuclear fractions Maitane Ortiz-Virumbrales, Marta Ruiz, Eugene Hone, Georgia Dolios, Rong Wang, Andrika Morant, Jessica Kottwitz, Laurie J Ozelius, Sam Gandy, Michelle E Ehrlich ...
Convection-Enhanced Delivery of AAV2-PrPshRNA in Prion-Infected Mice Misol Ahn, Krystyna Bajsarowicz, Abby Oehler, Azucena Lemus, Krystof Bankiewicz, Stephen J. DeArmond PLoS One. 2014; 9(5): e98496. Published online 2014 May 27. doi: 10.1371/journal.pone.0098496 PMCID: PMC4035323 ...