Publications

Selective activation of a putative reinforcement signal conditions cued interval timing in primary visual cortex Cheng-Hang Liu, Jason E. Coleman, Heydar Davoudi, Kechen Zhang, Marshall G. Hussain Shuler Curr Biol. Author manuscript; available in PMC 2016 Jun 15....

Acute cerebellar knockdown of Sgce reproduces salient features of myoclonus-dystonia (DYT11) in mice Samantha Washburn, Rachel Fremont, Maria Camila Moreno-Escobar, Chantal Angueyra, Kamran Khodakhah eLife. 2019; 8: e52101. Published online 2019 Dec 23. doi:...

Aberrant Purkinje cell activity is the cause of dystonia in a shRNA-based mouse model of Rapid Onset Dystonia-Parkinsonism Rachel Fremont, Ambika Tewari, Kamran Khodakhah Neurobiol Dis. Author manuscript; available in PMC 2016 Oct 1. Published in final edited form as:...

Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intracerebroventricular injection Sean L. Hammond, Ashley N. Leek, Evan H. Richman, Ronald B. Tjalkens PLoS One. 2017; 12(12): e0188830. Published online 2017 Dec 15. doi:...

BACE2, a conditional β-secretase, contributes to Alzheimer’s disease pathogenesis Zhe Wang, Qin Xu, Fang Cai, Xi Liu, Yili Wu, Weihong Song JCI Insight. 2019 Jan 10; 4(1): e123431. Published online 2019 Jan 10. doi: 10.1172/jci.insight.123431 PMCID:...

Klotho controls the brain–immune system interface in the choroid plexus Lei Zhu, Liana R. Stein, Daniel Kim, Kaitlyn Ho, Gui-Qiu Yu, Lihong Zhan, Tobias E. Larsson, Lennart Mucke Proc Natl Acad Sci U S A. 2018 Nov 27; 115(48): E11388–E11396. Published online 2018 Nov...

Integration of a CD19 CAR into the TCR Alpha Chain Locus Streamlines Production of Allogeneic Gene-Edited CAR T Cells Daniel T. MacLeod, Jeyaraj Antony, Aaron J. Martin, Rachel J. Moser, Armin Hekele, Keith J. Wetzel, Audrey E. Brown, Melissa A. Triggiano, Jo Ann Hux,...

Dystonia type 6 gene product Thap1: identification of a 50 kDa DNA-binding species in neuronal nuclear fractions Maitane Ortiz-Virumbrales, Marta Ruiz, Eugene Hone, Georgia Dolios, Rong Wang, Andrika Morant, Jessica Kottwitz, Laurie J Ozelius, Sam Gandy, Michelle E...

Convection-Enhanced Delivery of AAV2-PrPshRNA in Prion-Infected Mice Misol Ahn, Krystyna Bajsarowicz, Abby Oehler, Azucena Lemus, Krystof Bankiewicz, Stephen J. DeArmond PLoS One. 2014; 9(5): e98496. Published online 2014 May 27. doi: 10.1371/journal.pone.0098496...

Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase J. Sanchez–Padilla, J.N. Guzman, E. Ilijic, J. Kondapalli, D.J. Galtieri, B. Yang, S. Schieber, W. Oertel, D. Wokosin, P. T. Schumacker, D. J. Surmeier Nat Neurosci....

Peripheral Brain Derived Neurotrophic Factor Precursor Regulates Pain as an Inflammatory Mediator Cong Luo, Xiao-Lin Zhong, Fiona H. Zhou, Jia-yi Li, Pei Zhou, Jun-Mei Xu, Bo Song, Chang-Qi Li, Xin-Fu Zhou, Ru-Ping Dai Sci Rep. 2016; 6: 27171. Published online 2016...

Long-term Expression of Apolipoprotein B mRNA-specific Hammerhead Ribozyme via scAAV8.2 Vector Inhibits Atherosclerosis in Mice Hersharan Nischal, Hua Sun, Yuchun Wang, David A Ford, Ying Cao, Peng Wei, Ba-Bie Teng Mol Ther Nucleic Acids. 2013 Oct; 2(10): e125....

Disruption in dopaminergic innervation during photoreceptor degeneration Elena Ivanova, Christopher W Yee, Botir T Sagdullaev J Comp Neurol. Author manuscript; available in PMC 2017 Apr 15. Published in final edited form as: J Comp Neurol. 2016 Apr 15; 524(6):...

Maladaptive Downregulation of Autonomous Subthalamic Nucleus Activity following the Loss of Midbrain Dopamine Neurons Eileen L. McIver, Jeremy F. Atherton, Hong-Yuan Chu, Kathleen E. Cosgrove, Jyothisri Kondapalli, David Wokosin, D. James Surmeier, Mark D. Bevan Cell...

The matricellular protein CCN5 inhibits fibrotic deformation of retinal pigment epithelium Aeri Yoon, Sora Im, Juyeon Lee, Daeho Park, Dong Hyun Jo, Jin Hyoung Kim, Jeong Hun Kim, Woo Jin Park PLoS One. 2018; 13(12): e0208897. Published online 2018 Dec 20. doi:...

Closed-loop functional optogenetic stimulation Shriya S. Srinivasan, Benjamin E. Maimon, Maurizio Diaz, Hyungeun Song, Hugh M. Herr Nat Commun. 2018; 9: 5303. Published online 2018 Dec 13. doi: 10.1038/s41467-018-07721-w PMCID: PMC6294002

Exosomes derived from rAAV/AFP-transfected dendritic cells elicit specific T cell-mediated immune responses against hepatocellular carcinoma Jieyu Li, Shenglan Huang, Zhifeng Zhou, Wansong Lin, Shuping Chen, Mingshui Chen, Yunbin Ye Cancer Manag Res. 2018; 10:...

Suppression of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Function in Thalamocortical Neurons Prevents Genetically Determined and Pharmacologically Induced Absence Seizures François David, Nihan Çarçak, Szabina Furdan, Filiz Onat, Timothy Gould, Ádám...

PACAP neurons in the ventral premammillary nucleus regulate reproductive function in the female mouse Rachel A Ross, Silvia Leon, Joseph C Madara, Danielle Schafer, Chrysanthi Fergani, Caroline A Maguire, Anne MJ Verstegen, Emily Brengle, Dong Kong, Allan E Herbison,...

Site-Specific Gene Editing of Human Hematopoietic Stem Cells for X-Linked Hyper-IgM Syndrome Caroline Y. Kuo, Joseph D. Long, Beatriz Campo-Fernandez, Satiro de Oliveira, Aaron R. Cooper, Zulema Romero, Megan D. Hoban, Alok V. Joglekar, Georgia R. Lill, Michael L....